phosphatidyl choline

phosphatidyl choline
The major phospholipid of most mammalian cell membranes where the 1-acyl residue is normally saturated and the 2-acyl residue unsaturated. Choline is attached to phosphatidic acid by a phosphodiester linkage. Major synthetic route is from diacyl glycerol and CDP-choline. Forms monolayers at an air/water interface, and forms bilayer structures (liposomes) if dispersed in aqueous medium. A zwitterion over a wide pH range. Readily hydrolyzed in dilute alkali.

Dictionary of molecular biology. 2004.

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